Ganesh Pyne's painting dwell on themes of death and his canvases rarely has light backgrounds. Blue and black being his favourite, he adorns them with motifs in tempera which are rich in imageries and symbolism. He had his art education from Govt. College of Art & Craft, and he draws inspiration for his work from Rembrandt, Klee and from movies made by Fellini and Bergman. His signature style of work is shaped from his own experiences of solitude, alienation, pain horror and moods of tenderness and serenity. He is one of the most sought after painter in Indian contemporary art and has shown his works all around the globe, with a vast collection preserved among eminent art collectors in India and abroad.